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The Liz Moody Podcast

The REAL Story Of Ozempic, Weight Loss, And The Metabolic Crisis 94% Of Us Are Facing

Wed Jul 10 2024
metabolic healthOzempicobesityGLP-1 receptor agonistsultra-processed foodsholistic healthsystemic issuesbiomarkersdetoxification systemsskincarecollagen peptides

Description

This episode explores the topic of metabolic health and its relationship with medications like Ozempic. It covers various factors contributing to obesity, the impact of Ozempic on metabolic health biomarkers, strategies to increase GLP-1 levels naturally, the influence of ultra-processed foods on cravings and satiety, holistic approaches to health, systemic issues affecting metabolic health, key biomarkers for metabolic health, detoxification systems, skincare and collagen peptides, the rise of ultra-processed foods, and insights from the book 'Good Energy' on improving metabolic health. The episode emphasizes the importance of understanding metabolic health beyond just obesity and highlights the complex relationship between health, industry, and consumer choices.

Insights

Ozempic induces caloric restriction leading to weight loss and improves insulin sensitivity which can impact visceral fat associated with poor health.

Ozempic is a popular topic of discussion, with debates on its impact on metabolic health and weight loss.

GLP-1 receptor agonists like Ozempic work by stimulating insulin secretion, sensitizing insulin action, delaying gastric emptying, and reducing hunger cravings to aid in weight loss and diabetes management.

Obesity rates in America have drastically increased over the past 150 years, with up to 50% of people being obese and 75% overweight or obese.

Research suggests that Ozempic may have a positive impact on conditions like polycystic ovarian syndrome and depression, but there are also concerns about side effects and cost compared to alternative lifestyle strategies.

The impact of GLP-1 receptor agonists on the microbiome is varied and not fully understood due to limited and heterogeneous studies.

Increasing GLP-1 levels naturally through dietary strategies like consuming high-fiber foods, antioxidants, amino acids, probiotic-rich foods, curcumin, green tea, and certain nuts can be healthful.

GLP-1 acts in the body by decreasing gastric emptying and making us feel fuller for longer.

Switching to whole foods can significantly reduce cravings and overeating by stimulating satiety hormones.

Eating nutrient-dense whole foods stimulates satiety mechanisms, while ultra-processed foods are designed to make us insatiable.

GLP-1 is an incretin hormone that impacts the body by reducing cravings and hunger in the brain, protecting pancreatic cells, regulating insulin secretion, inhibiting glucagon, and slowing gastric emptying to promote feelings of fullness.

Using medication for weight loss can be a helpful jumpstart but should be part of a holistic plan including healthy habits like cooking with whole foods and resistance training.

Metabolic health plays a crucial role in overall well-being and is linked to various health conditions

Eating real food, focusing on sleep, and walking are more effective strategies for health than pharmaceutical solutions like Ozempic

Optimal metabolic health requires thorough investigation into various factors affecting energy production in the body.

Key biomarkers to track for metabolic health include fasting glucose, triglycerides, HDL cholesterol, blood pressure, waist circumference, and hemoglobin A1c.

Simple daily habits, like using natural cleaning supplies and skincare products, can support cellular health.

Our body has incredible detoxification systems that constantly filter out toxins.

Improving mitochondrial health involves knowing biomarkers, avoiding ultra-processed foods, and focusing on movement over exercise

Osmia skincare products offer a 20% discount for listeners using the code Liz Moody

Chapters

  1. Understanding Metabolic Health and Ozempic
  2. Factors Contributing to Obesity and the Role of Ozempic
  3. The Impact of Ozempic on Metabolic Health Biomarkers
  4. Understanding GLP-1 and Strategies to Increase Its Levels
  5. The Influence of Ultra-Processed Foods on Cravings and Satiety
  6. Holistic Approaches to Health and the Role of Pharmaceutical Solutions
  7. The Influence of Systemic Forces on Health and Metabolic Health Biomarkers
  8. Addressing Systemic Issues and Tracking Biomarkers for Metabolic Health
  9. Key Biomarkers for Metabolic Health and Factors Affecting Energy Production
  10. Detoxification Systems and Small Changes for Cellular Health
  11. Skincare and the Role of Collagen Peptides
  12. The Rise of Ultra-Processed Foods and Unhealthy Eating Habits
  13. The Book 'Good Energy' and Strategies for Metabolic Health
Summary
Transcript

Understanding Metabolic Health and Ozempic

00:00 - 07:26

  • Ozempic is a popular topic of discussion, with debates on its impact on metabolic health and weight loss.
  • Metabolic health expert Dr. Casey Means discusses the importance of understanding metabolic health beyond just obesity.
  • Excess weight can have implications for health beyond metabolic issues, such as joint pain, surgical risks, respiratory issues, and infections.
  • Different types of fat like subcutaneous, visceral, and intracellular fat have varying impacts on health.
  • Ozempic induces caloric restriction leading to weight loss and improves insulin sensitivity which can impact visceral fat associated with poor health.

Factors Contributing to Obesity and the Role of Ozempic

07:05 - 14:08

  • Obesity rates in America have drastically increased over the past 150 years, with up to 50% of people being obese and 75% overweight or obese.
  • The rise in obesity is linked to mitochondrial dysfunction caused by various factors in the modern environment.
  • Eight main pillars contributing to mitochondrial dysfunction include poor diet, sedentary behavior, sleep deprivation, emotional stress, synthetic toxins, light exposure changes, temperature variations, and medication use.
  • While medications like Ozempic can help improve metabolic health by addressing certain aspects like processed food consumption, they do not address all factors impacting mitochondrial function and overall cellular health.
  • GLP-1 receptor agonists like Ozempic work by stimulating insulin secretion, sensitizing insulin action, delaying gastric emptying, and reducing hunger cravings to aid in weight loss and diabetes management.
  • These medications may also have additional effects on inflammation levels, cholesterol levels, blood pressure reduction, kidney health improvement, stroke and heart attack risk reduction.

The Impact of Ozempic on Metabolic Health Biomarkers

13:43 - 21:17

  • The impact of GLP-1 receptor agonists on the microbiome is varied and not fully understood due to limited and heterogeneous studies.
  • Ozempic shows positive effects on metabolic health biomarkers like waist circumference and fasting glucose.
  • There are concerns about focusing solely on specific biomarkers rather than addressing holistic health issues in society.
  • While Ozempic may improve certain biomarkers in metabolic health, these improvements often reverse when individuals stop taking the medication.
  • Research suggests that Ozempic may have a positive impact on conditions like polycystic ovarian syndrome and depression, but there are also concerns about side effects and cost compared to alternative lifestyle strategies.
  • When people discontinue Ozempic, they may experience increased hunger due to changes in GLP-1 levels, leading to challenges in managing cravings.

Understanding GLP-1 and Strategies to Increase Its Levels

27:55 - 34:55

  • GLP-1 acts in the body by decreasing gastric emptying and making us feel fuller for longer.
  • GLP-1 is secreted by L-cells in the gut and can be influenced by lifestyle factors.
  • People produce varying amounts of GLP-1, with those with type 2 diabetes or fatty liver disease potentially producing less naturally.
  • Environmental factors may play a role in changing GLP-1 production, impacting weight gain trends.
  • Increasing GLP-1 levels naturally through dietary strategies like consuming high-fiber foods, antioxidants, amino acids, probiotic-rich foods, curcumin, green tea, and certain nuts can be healthful.
  • Strategies to increase GLP-1 include promoting L-cell differentiation through high-fiber diets and short-chain fatty acids, maximizing thylakoids for more GLP-1 production per L-cell, and inhibiting DPP-4 to retain GLP-1 longer using foods like dark berries and herbs.

The Influence of Ultra-Processed Foods on Cravings and Satiety

34:31 - 41:43

  • Eating nutrient-dense whole foods stimulates satiety mechanisms, while ultra-processed foods are designed to make us insatiable.
  • Processed food companies use scientists to hijack reward circuitry in the brain and create craveable foods.
  • High fructose corn syrup drives hunger and aggressive food-seeking behavior, leading to overeating and obesity.
  • Switching to whole foods can significantly reduce cravings and overeating by stimulating satiety hormones.
  • Frontloading meals with real, nutrient-rich foods promotes satiety and reduces hunger effortlessly.
  • Science is used both to engineer craveable foods and to develop solutions like Ozempic, highlighting a complex relationship between health, industry, and consumer choices.

Holistic Approaches to Health and the Role of Pharmaceutical Solutions

20:56 - 28:21

  • Using medication for weight loss can be a helpful jumpstart but should be part of a holistic plan including healthy habits like cooking with whole foods and resistance training.
  • Non-toxic laundry detergent like Molly's Suds can be beneficial for skin health and overall well-being by avoiding harmful chemicals.
  • O3 Ultra Pure Fish Oil from Puri is a high-quality supplement that undergoes rigorous testing to ensure purity and safety, offering benefits for brain, heart, and skin health.
  • GLP-1 is an incretin hormone that impacts the body by reducing cravings and hunger in the brain, protecting pancreatic cells, regulating insulin secretion, inhibiting glucagon, and slowing gastric emptying to promote feelings of fullness.

The Influence of Systemic Forces on Health and Metabolic Health Biomarkers

41:15 - 48:09

  • Eating real food, focusing on sleep, and walking are more effective strategies for health than pharmaceutical solutions like Ozempic
  • There is a significant financial incentive in the healthcare and ultra-processed food industries to keep people sick and addicted to their products
  • Opting for fresh, real food and lifestyle changes can be a disruptive but beneficial escape from the current unhealthy societal norms
  • Metabolic health plays a crucial role in overall well-being and is linked to various health conditions
  • Lumen offers a handheld metabolic coach that measures metabolic health through breath analysis and provides personalized guidance for improving metabolism
  • Colostrum, the first nutrition humans receive, has potential benefits for allergies, gut health, immune system regulation, skin health, and energy levels
  • Armour Colostrum is sustainably sourced with high bioavailability and purity standards

Addressing Systemic Issues and Tracking Biomarkers for Metabolic Health

47:53 - 54:40

  • Personal responsibility for health is discussed in the context of systemic forces working against individuals.
  • The current environment makes it challenging to prioritize health due to factors like job demands and pervasive technology.
  • Systemic issues such as farm bills, school lunch programs, and pharmaceutical advertising contribute to poor health outcomes in the U.S.
  • Educating people on basic metabolic health principles and focusing on evidence-based strategies can lead to improved health outcomes.
  • Policy changes at the governmental level are seen as high leverage opportunities to address metabolic health issues and improve public health.
  • Tracking basic biomarkers regularly is recommended as a way to monitor progress towards better metabolic health.

Key Biomarkers for Metabolic Health and Factors Affecting Energy Production

54:12 - 1:00:54

  • Key biomarkers to track for metabolic health include fasting glucose, triglycerides, HDL cholesterol, blood pressure, waist circumference, and hemoglobin A1c.
  • Meeting specific ranges for these biomarkers can indicate metabolic health and reduce the risk of chronic diseases.
  • Changes in diet and lifestyle can significantly impact these biomarkers within a month.
  • Factors like stress, sleep apnea, resistance training, and micronutrient levels play crucial roles in metabolic health.
  • Further lab tests may include fasting insulin levels, CRP for inflammation, liver function testing, uric acid levels, vitamin D levels, and hormone testing.
  • Optimal metabolic health requires thorough investigation into various factors affecting energy production in the body.

Detoxification Systems and Small Changes for Cellular Health

1:00:35 - 1:07:12

  • Our body has incredible detoxification systems that constantly filter out toxins.
  • Redirecting energy towards healthier choices can lead to significant health improvements.
  • Making small changes in purchasing decisions, like choosing organic or natural products, can reduce toxin exposure.
  • Spending more time outdoors can have a positive impact on health and well-being.
  • Simple daily habits, like using natural cleaning supplies and skincare products, can support cellular health.

Skincare and the Role of Collagen Peptides

1:06:50 - 1:14:21

  • Osmia skincare products offer a 20% discount for listeners using the code Liz Moody
  • Collagen peptides have benefits for skin, hair, and joint health supported by research
  • Great Lakes Wellness Collagen Peptides are tasteless and dissolve well in beverages
  • Improving mitochondrial health involves knowing biomarkers, avoiding ultra-processed foods, and focusing on movement over exercise
  • Ultra-processed foods can lead to inflammation due to being foreign to the body

The Rise of Ultra-Processed Foods and Unhealthy Eating Habits

1:13:54 - 1:20:50

  • Whole wheat bread is not considered ultra-processed as it contains all parts of the grain, unlike white flour which lacks key nutrients and leads to blood sugar spikes.
  • Ultra-processed foods are designed to make us crave more food by removing essential nutrients and adding harmful additives like preservatives and artificial flavorings.
  • The rise of ultra-processed foods is linked to societal factors such as a lack of awe for the human body, urbanization, technological advancements, and a focus on financial productivity over well-being.
  • The root cause of unhealthy eating habits may stem from a disconnect with the miraculous nature of human existence, leading individuals to seek quick fixes like dopamine-inducing activities instead of nourishing their bodies.

The Book 'Good Energy' and Strategies for Metabolic Health

1:20:29 - 1:26:35

  • The podcast guest discusses her book 'Good Energy' which focuses on metabolism and limitless health.
  • The book is divided into three parts: understanding metabolic dysfunction, exploring biomarkers for metabolic health, and providing evidence-based strategies to improve metabolic health.
  • The second half of the book includes 30 recipes and a four-week plan for enhancing metabolic health.
  • The upcoming episode will cover exercise, nutrition, lifestyle support strategies, the role of hormones in weight management, weight loss drugs for children, and more related to metabolic health.
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