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    Nature Podcast

    Alphafold 3.0: the AI protein predictor gets an upgrade

    Wed May 08 2024
    scienceclocksphysicsprotein prediction

    Description

    Deep dive into the world of science with Nature+. Nature Plus, the key to unlocking the world's most significant scientific advances. Subscribe today at go.nature.com/plus. Acast powers the world's best podcasts.

    Insights

    New Clocks for Precision and Physics

    Scientists are developing a new type of clock that shows potential for greater precision and allows researchers to test the laws of physics.

    Nuclear Clocks and Thorium 229

    Nuclear clocks use energy states in the nucleus, and researchers are narrowing down the exact frequency required for thorium 229.

    Advancements in Protein Prediction

    Alpha Fold 3 can accurately model complex combinations of proteins and other molecules, with potential applications in drug discovery and understanding protein interactions.

    Chapters

    1. Introduction
    2. Film Club
    3. Clocks and Physics
    4. Nuclear Clocks
    5. Thorium 229
    6. Advancements in Protein Prediction
    Summary
    Transcript

    Introduction

    00:01 - 00:46

    • Deep dive into the world of science with Nature+
    • Nature Plus, the key to unlocking the world's most significant scientific advances

    Film Club

    00:50 - 01:12

    • Join Frank Film Club with Maisie Williams
    • Watch and discuss films each week

    Clocks and Physics

    02:13 - 03:43

    • Scientists are developing a new type of clock that shows potential for greater precision
    • The new clock could also allow researchers to test the laws of physics

    Nuclear Clocks

    03:44 - 04:27

    • Atomic clocks use electron energy states, while nuclear clocks use energy states in the nucleus
    • Nuclear clocks have been difficult to make due to the small energy differences and precise frequency requirements

    Thorium 229

    04:27 - 05:38

    • Thorium 229 is a nucleus that has a small energy difference for nudging it to a higher energy state
    • Researchers are narrowing down the exact frequency required to trigger the energy transition

    Advancements in Protein Prediction

    11:48 - 12:13

    • Alpha Fold 3 can accurately model complex combinations of proteins and other molecules
    • The tool has potential applications in drug discovery and understanding protein interactions
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