The Peter Attia Drive

The Peter Attia Drive

Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.

The Peter Attia Drive

Mon Jun 24 2024

Exercise for aging people: where to begin, and how to minimize risk while maximizing potential | Peter Attia, M.D.

exerciseagingfitnessstrength trainingfall prevention

The podcast episode provides practical advice on starting exercise for individuals aged 50 and above. It emphasizes the importance of exercise for longevity and highlights specific age milestones where considerations for strength, vestibular changes, and fall risks become critical. The episode covers topics such as the four pillars of aging, population-based reductions in activity, determining exercise intensity, the importance of VO2 Max for longevity, effective training strategies, fall risk and injury prevention, preventing falls and fractures, bone health and strength training, and optimizing protein intake and exercise.

The Peter Attia Drive

Mon Jun 17 2024

AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more

Ask Me AnythingCognitive DeclineMetabolic HealthSleep

This episode is a sneak peek of the Ask Me Anything (AMA) episode of the Drive podcast. The AMA covers a wide range of topics including the prevention of cognitive decline, the relationship between cardiovascular disease and Alzheimer's disease, and nutrition. Other topics discussed are blood pressure, step requirements per day, and standing versus sitting desks.

The Peter Attia Drive

Mon Jun 10 2024

Heart rate variability: how to measure, interpret, and utilize HRV for training and health optimization | Joel Jamieson

Heart Rate VariabilityHRV MeasurementAutonomic Nervous SystemTrainingLongevity

The podcast explores the science of longevity and the role of heart rate variability (HRV) in training and overall health. It covers topics such as the history and evolution of HRV measurement, different tools for measuring HRV, optimal locations for HRV measurement, the autonomic nervous system's role in HRV, the impact of lifestyle choices on HRV, using data-driven insights for training, monitoring heart rate recovery and conditioning, balancing anaerobic and aerobic training, HRV and medication effects, and the importance of monitoring HRV for overall health. The episode provides practical tips and recommendations for HRV monitoring and training.

The Peter Attia Drive

Mon Jun 03 2024

NEW: Introducing quarterly podcast summaries - Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more

interviewskey insightsmuscle protein synthesisanabolic resistancepremium membership

This episode covers a range of topics including preparing for interviews, key insights from past episodes, factors influencing muscle protein synthesis, anabolic resistance, and premium membership benefits. The importance of staying active to prevent muscle loss is emphasized. Listeners are encouraged to provide feedback on the new AMA episode format. Contact information and subscription details are provided.

The Peter Attia Drive

Mon May 27 2024

A breakthrough in Alzheimer’s disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer's disease | Dena Dubal, M.D., Ph.D.

ClothoLongevityBrain HealthCognitive EnhancementAlzheimer's Disease

The episode explores the science behind Clotho, a protein or gene associated with longevity and brain health. The discussion covers its role in regulating cognitive functions, brain health, and potential treatment for neurodegenerative diseases like Alzheimer's. Key insights include the effects of aging on Clotho levels, the relationship between Clotho and platelets, and the potential use of Clotho as a treatment for Parkinson's disease and Lewy body dementia. The episode also delves into the KLVS gene variant and its association with cognitive enhancement and reduced Alzheimer's risk. Additionally, it discusses Clotho as a potential diagnostic biomarker for chronic kidney disease and its broader implications for cancer, cardiovascular disease, and kidney disease. The episode concludes with the challenges of Alzheimer's research and the importance of philanthropy in funding innovative science projects.

The Peter Attia Drive

Mon May 20 2024

Confronting a metabolic epidemic: understanding liver health and how to prevent, diagnose, and manage MAFLD and liver disease | Julia Wattacheril, M.D., M.P.H.

Liver PhysiologyLiver DiseaseLiver TransplantsAlcohol and Liver HealthMetabolic-Associated Liver Disease

This episode explores the science of liver physiology, liver diseases, and the impact of lifestyle on liver health. Topics covered include liver transplants, alcohol's impact on the liver, metabolic-associated liver disease, fructose metabolism, and future treatments for liver disease. The episode emphasizes the importance of proactive liver health monitoring and lifestyle interventions for improving metabolic health.

The Peter Attia Drive

Mon May 13 2024

AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it

inflammationagingdiseaseschronic inflammationinflammatory biomarkers

The episode covers the topic of inflammation, including its definition and connection to aging and diseases. It discusses ways to identify chronic inflammation and strategies to address it through diet, exercise, sleep, and stress management. The impact of inflammation on disease risk and mortality is explored, highlighting the correlation between high levels of inflammatory biomarkers and increased risk. The importance of a holistic approach to targeting inflammation is emphasized.

The Peter Attia Drive

Mon May 06 2024

Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?

LongevityAgingGeoprotective DrugsRapamycinMetformin

The podcast celebrates its 300th episode by covering various topics categorized as proven, promising, fuzzy, noise, and nonsense based on listener feedback. Topics discussed include geoprotective drugs like rapamycin and metformin, NAD precursors, VO2 max, muscle mass, blood flow restriction, stem cells, and nutrition aspects like fasting, sugar substitutes, and red meat's role in cancer.

The Peter Attia Drive

Mon Apr 29 2024

Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna’s death

Ayrton SennaFormula 1MonacoQualifyingBrazil

The podcast episode commemorates the 30th anniversary of Ayrton Senna's death on May 1st, 1994. The discussion between Peter Atia and Dax Shepard focuses on Senna's career, life, death, and lasting impact on Formula 1. They discuss Senna's exceptional qualifying skills, his dominance at Monaco, his legacy in Brazil, and the controversy surrounding his fatal crash at Imola. The episode also explores the current state of Formula 1, the greatest F1 drivers of all time, and insights into Max Verstappen's driving style. Throughout the episode, personal reflections and anecdotes are shared by the hosts.

The Peter Attia Drive

Mon Apr 22 2024

Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D.

protein metabolismmuscle protein synthesisnutritionexerciseendurance exercising

This episode explores the science behind protein metabolism, muscle protein synthesis, and optimizing nutrition for muscle health. Topics include the role of insulin, glucose, and protein in endurance exercising, measuring energy expenditure and carbohydrate oxidation rate, intramyocellular lipid utilization and post-exercise replenishment, glucose homeostasis and fat oxidation, protein synthesis and metabolism, digestion and absorption of protein, factors affecting protein turnover, optimal protein intake and recovery, muscle loss and overall health, importance of physical activity, optimizing muscle protein synthesis, protein supplementation and overall diet quality, weight loss and muscle maintenance, muscle response to exercise and anabolic resistance, muscle loss and physical activity, androgen deprivation therapy and muscle loss, collagen and muscle protein synthesis, plant-based proteins and protein turnover.

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